BIOS602 Resources: Epidemiology: Inference & Regression models

Lecture Notes

Epidemiology texts

Observation and Inference (A Walker1991)

• Link

PDQ-Epidemiology (D Streiner, G Norman and H Munroe-Blum; 1989)

• Ch 1 | Ch 2 | Ch 3 | Ch 4

Primer of Epidemiology (G Friedman; 1974... newer, larger, editions available)

• Preface 1.Intro to Epi 2.Basic Measurements in Epi 3.Observations Used in Epi
  4.Basic Methods of Study 5 Descriptive Studies 6 Prevalence Studies
  7.Case-Control Studies 8.Incidence or Cohort Studies 9.Experimental Studies
  10.Clinical Studies of Disease Outcome 11.Making Sense Out of Statistical Associations
  12.How to Carry Out a Study 13.Epi & Patient Care 14.Epi, Medical Care & Health of the Community
  Index
  

Statistical texts

Statistical Methods in Cancer research, vol I (N Breslow and N Day 1980)

• Chapter 2 Fundamental Measures of Disease Occurrence and Association
• Chapter 4 Classical Methods of Analysis of Grouped Data
• Chapter 7 Conditional Logistic Regression for Matched Sets

Statistical Methods in Cancer research, volume II (N Breslow and N Day 1987)

• front matter
• Chapter 1: The Role of Cohort Studies in Cancer Epidemiology
• Chapter 2: Rates and Rate Standardization
• Chapter 3: Comparisons among Exposure Groups
• Chapter 4: Fitting Models to Grouped Data
• Chapter 5: Fitting Models to Continuous Data

Statistical Models in Epidemiology (D Clayton and M Hills 1993)

• LINK

Survival Analysis: Techniques for Censored & Truncated Data (Klein & Moeschberger)

• LINK

Excerpts: Generalized Linear Models (P McCullagh and J Nelder 1989)

• Table of Contents
• 7.3 Hypergeometric distributions; 7.4 Some applications involving binary data
• 13.5 Cox's proportional-hazards model

Theoretica Epidemiology (O. Miettenen, 1985)

• Appendix 4: Crude, Adjusted and Standardized Rates

Articles

• Measurement of Occupational Mortality - Liddell 1960
   
• Progress Against Cancer. Bailar and Smith NEJM 1986
• Cancer Undefeated. Bailar and Gornik, New Engl J Med 1997;336:1569-74.
   
• The Analysis of Prospective Studies of Disease Aetiology Clayton1982. see section 6 p 2140 for
  a derivation of MLE of common rate ratio, and how close Mantel-Haenszel estimator comes to it.

Datasets

Québec mortality data , 1971, 1976, 1980-1992 2002

• Females(.txt)   |   Males(.txt)   |   R(.txt)   |   SAS(.txt)

Normal Breslow's webpage

• link

Longevity of actors/actresses who have been nominated for an Oscar

• dataset(.csv)   |   article

FIFA dataset [study of effect of altitude on performance]

• fifa.csv 90 records (all pairs)   Article

Example 3.11, Table 3.14, (arsenic exposure, 13 strata), Breslow and Day Vol II

• B-and-D-II-example3-11.txt data for R.

Example, p 137 Breslow and Day Vol I, and Table 4.3 page 145 [c-c,6 strata]

• Table-4-3-BD-I.txt data for R.

Example 5.1, p 187-190, Breslow and Day Vol I [BrCa Estrogen, 23 risksets]

• Data (.txt)  |   R code (.txt)

WOBURN LEUKEMIA dataset and R code for MLE

• WoburnData-R.txt     |     link to JASA article [Lagakos/Wessen/Zelen '86]

Software, computer code ...

For Person-Years Analyses

• link to pamcomp (Person-years And Mortality COMputation Program)
• link to Epi package for R
• R code for Breslow and Day Ch 3 analyses of Montana data
• U.S. Death Rates
• Montana Data
  
  
• Oscar longevity data (R code)
  
• Re-analysis -- sylvestre/huszti/hanley article & appendix
  
  
• Titanic longevity data
  US death rates 5 x 5 from Berkeley Mortality Database
  Titanic longevity data (R code) 2008
  Titanic longevity data (R code) 2009
  Titanic longevity data (R code) 2015
  Titanic longevity data (R code) 2017